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KW-2449 has significant activity and warrants clinical study in leukemia patients with FLT3 mutations as well as Imatinib-resistant mutations
1793053-37-8
Formula: C18H12O3
5-10 µM in vitro and cellular assays
TAK-875 is currently in clinical trials for the treatment of type 2 diabetes mellitus
Hoechst 33258 trihydrochloride - CAS# 23491-45-4 aloxon KW-2449 has significant activity andBisbenzimide, also known as Pibenzimol, Hoechst 33258, is a cell permeable, benzimidazole dye that binds to the minor groove of double stranded DNA with preference for adenine and thymine rich sequences. Product information CAS Number: 23491 45 4 Molecular Weight: 533. 88 Formula: C25H27Cl3N6O Synonym: bisBenzimide H 33258 H 33258 Hoechst33258 Hoechst 33258 Chemical Name: 4 {6 [6 (4 methylpiperazin 1 yl) 1H 1,3 benzodiazol 2 yl] 1H 1,3 benzodiazol 2
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