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It was demonstrated in February 2009 that fasudil could also be used to enhance memory and improve the prognosis of Alzheimers patients
InChi: InChI=1S/C23H15ClF2N2O2/c24-16-8-6-15(7-9-16)23-18-4-2-1-3-17(18)22(30)28(23)12-11-27(23)21(29)14-5-10-19(25)20(26)13-14/h1-10
Smiles: C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OCCC3C=C(O)C(O)=CC=3)[C@H](O)[C@@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H]2OC(=O)/C=C/C2=CC(O)=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1O
Desai-Krieger D
Mijatovic T
AZD4547 ustat It was demonstrated in FebruaryAZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation,
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