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and voltage-gated L-type calcium channels (E-value≥-6
Smiles: CC1(C)CN(C(C(=O)NO)N(C1)S(=O)(=O)C1C=CC(=CC=1)OC)S(=O)(=O)C1C=CC(=CC=1)OC
Zaurategrast
Montero JL
and prevents DMBA-induced inhibition of cell growth
PF-06835919 Catalog No.:M33609-C and voltage-gated L-type calcium channelsPF 06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF 06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to
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