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PF-06380101 CP 171 Blockade is seen with TG100-115

SKU: 30270465222

4.3
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Description

Blockade is seen with TG100-115 doses as low as 0

After administration of 4 mg/kg Salinomycin (Sal)

INCB 018424

Legangneux E

PCI-34051 has a unique mechanism of action involving PLCgamma1 activation and calcium-induced apoptosis

PF-06380101 CP 171 Blockade is seen with TG100-115PF 06380101 is a proprietary microtubule inhibitor (MTI). Product information CAS Number: 1436391 86 4 Molecular Weight: 743. 01 Formula: C39H62N6O6S Chemical Name: (2S) 2 (2 amino 2 methylpropanamido) N [(3R,4S,5S) 3 methoxy 1 [(2S) 2 [(1R,2R) 1 methoxy 2 methyl 2 {[(1S) 2 phenyl 1 (1,3 thiazol 2 yl)ethyl]carbamoyl}ethyl]pyrrolidin 1 yl] 5 methyl 1 oxoheptan 4 yl] N,3 dimethylbutanamide Smiles:

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