TMC647055 Choline salt 5041 sodium for 12 weeks) alleviates hepatic

for 12 weeks) alleviates hepatic steatosis

InChi: InChI=1S/C7H5ClF3NO2S2/c8-5-3-12-7(15-5)16(13

5 mg/kg for 4 weeks displays potent antitumor activity in the N-methyl-N-nitrosourea carcinogen-induced rat mammary carcinoma model

Chemical Name: ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1

cosmetics and pharmaceutical treatment

TMC647055 Choline salt 5041 sodium for 12 weeks) alleviates hepaticTMC647055 choline salt is a cell permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer dependent transcription assay. IC50 value: 34 nM Target: HCV NS5Bin vitro: TMC647055 is a novel and potent nonnucleoside inhibitor of the HCV NS5B RNA dependent RNA polymerase. TMC647055 shows high selectivity for HCV when evaluated with a broad panel of human DNA and RNA viruses. TMC647055 shows median EC50 changes