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Duocarmycin SA - CAS# 130288-24-3 10232 InChiKey: UVSMNLNDYGZFPF-UHFFFAOYSA-N

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Description

InChiKey: UVSMNLNDYGZFPF-UHFFFAOYSA-N

when added to human plasma

exhibiting 5-fold greater affinity than the cognate peptide H4K20Me1

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC2=CNC3=CC=CC=C23)NC(=O)[C@H](CC2C=CC=CC=2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@H](CO)[C@@H](C)O)NC(=O)[C@H](N)CC1C=CC=CC=1

Amlexanox (20 mg/kg) enhances osteoblast differentiation of BMSCs

Duocarmycin SA - CAS# 130288-24-3 10232 InChiKey: UVSMNLNDYGZFPF-UHFFFAOYSA-NDuocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro. Product information CAS Number: 130288 24 3 Molecular Weight: 477. 47 Formula: C25H23N3O7 Chemical Name: methyl (1R, 12S) 7

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