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c-Kit-IN-3 Size:Contact [email protected] for quotation InChi: InChI=1S/C22H22N2O3/c1-14-12-22(2

SKU: 15938211683

4.2
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Description

InChi: InChI=1S/C22H22N2O3/c1-14-12-22(2

Chemical Name: 2-[2-chloro-N-(3-chloro-4-methoxyphenyl)acetamido]-N-(2-phenylethyl)-2-(thiophen-2-yl)acetamide

31)32/h9-14

Oxytetracycline is an important member of the bacterial aromatic polyketide family

Formula: C22H39NO3

c-Kit-IN-3 Size:Contact [email protected] for quotation InChi: InChI=1S/C22H22N2O3/c1-14-12-22(2c Kit IN 3 (Compound 18) is a potent and selective c KIT kinase inhibitor with an IC50 of 4 nM. c Kit IN 3 displays great potencies against c KIT kinase and a broad spectrum of drug resistant mutants in the biochemical assay. c Kit IN 3 has improved bioavailability. c Kit IN 3 (Compound 18; 0. 1 10 M; 6 days; primary GIST patient cells) exhibits dose dependent antiproliferative effects. c Kit IN 3 (Compound 18; 0. 01 1 M; 24 hours; GIST T1, GIST T1

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