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GSK3368715 dihydrochloride 14893 InChiKey: KPURUIUXBWTRPB-UHFFFAOYSA-N

SKU: 17445815800

4.7
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Description

InChiKey: KPURUIUXBWTRPB-UHFFFAOYSA-N

and the low-threshold (T-type) Ca2+ currents are on average < 10% of control amplitude

RWJ-50271 is an inhibitor of LFA-1 (lymphocyte function-associated antigen-1) adhesion to soluble intercellular adhesion molecule (sICAM)

CAS Number: 175865-59-5

InChi: InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6

GSK3368715 dihydrochloride 14893 InChiKey: KPURUIUXBWTRPB-UHFFFAOYSA-NGSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S adenosyl L methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3. 1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5. 7 nM (PRMT6), 1. 7 nM (PRMT8)). GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti cancer activity. Product

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