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8(15):1375-89
7 nM in antagonism of monocyte chemoattractant protein-1 binding to hCCR2
2016 Jun 15
HIV-1 infection and latency-reversing agents bryostatin-1 and JQ1 disrupt amyloid beta homeostasis in human astrocytes
AZD8055 inhibits the phosphorylation of mTORC1 downstream targets (p70S6K and 4E-BP1) as well as phosphorylation of the mTORC2 downstream proteins (e
Methiothepin mesylate Size:2mg solid 8(15):1375-89Methiothepin mesylate is a potent and non selective 5 HT2 receptor antagonist, with pKds of 7. 10 (5 HT1A), 7. 28 (5HT1B), 7. 56 (5HT1C), 6. 99 (5HT1D), 7. 0 (5 HT5A), 7. 8 (5 HT5B), 8. 74 (5 HT6), and 8. 99 (5 HT7), and pKis of 8. 50 (5HT2A), 8. 68 (5HT2B), and 8. 35 (5HT2C). Product information CAS Number: 74611 28 2 Molecular Weight: 452. 65 Formula: C21H28N2O3S3 Synonym: Metitepine mesylate Ro 8 6837 mesylate Chemical Name: 1 methyl 4 [6