DBCO-NHS ester Size:10 mg solid NVP-TAE684 markedly reduces cell survival

NVP-TAE684 markedly reduces cell survival in both sensitive H3122 and H3122 CR cells

Robinson DJ

and t1/2 are 21

3 mg/kg bid

Smiles: CCS(=O)(=O)NC1OC(C2C=CC(Cl)=CC=2)=C(O)C=1O

DBCO-NHS ester Size:10 mg solid NVP-TAE684 markedly reduces cell survivalDBCO NHS ester is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1353016 71 3 Molecular Weight: 402. 40 Formula: C23H18N2O5 Chemical Name: 2,5 dioxopyrrolidin 1 yl 4 {2 azatricyclo[10. 4. 0. 0,]hexadeca 1(16),4,6,8,12,14 hexaen 10 yn 2 yl} 4 oxobutanoate Smiles: O=C(CCC(=O)ON1C(=O)CCC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12 InChiKey: XCEBOJWFQSQZKR UHFFFAOYSA N InChi: InChI=1S C23H18N2O5 c26