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ACY-738 Size:Contact [email protected] for quotation EN4 impairs the cell survival

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Description

EN4 impairs the cell survival of MYC transformed mammary epithelial MCF10A cells

Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly

10b-trihydroxy-3

ClH/c1-20-7-5-13(23-26-10-9-22)11-17(20)18(24)12-14-15-3-4-19(25)21(15

InChi: InChI=1S/C26H43N7O2/c1-30(2)10-7-17-35-24-19-22-21(18-23(24)34-5)25(27-20-8-13-32(4)14-9-20)29-26(28-22)33-12-6-11-31(3)15-16-33/h18-20H

ACY-738 Size:Contact [email protected] for quotation EN4 impairs the cell survivalACY 738 is a potent, selective and orally bioavailable HDAC6 inhibitor, with an IC50 of 1. 7 nM; ACY 738 also inhibits HDAC1, HDAC2, and HDAC3, with IC50s of 94, 128, and 218 nM. Product information CAS Number: 1375465 91 0 Molecular Weight: 270. 29 Formula: C14H14N4O2 Chemical Name: N hydroxy 2 [(1 phenylcyclopropyl)amino]pyrimidine 5 carboxamide Smiles: ONC(=O)C1C=NC(NC2(CC2)C2C=CC=CC=2)=NC=1 InChiKey: LIIWIMDSZVNYHY UHFFFAOYSA N InChi: InChI=1S

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