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ClH/c16-2-5-9(17)10(18)7(15-5)4-1-12-8-6(4)13-3-14-11(8)19
3800 and 6000 nM for MET
Williams VC
Smiles: CN1CCC[C@@H](C1)COC1=CC(=CC2CN(CCOC=21)C(=O)CC)C1=CC(OC)=C(C=C1)OC
Cefoselis hydrochloride exhibits good activity against a wide range of Gram-positive and Gram-negative organisms
SU14813 maleate - CAS# 849643-15-8 Size:Solid 10 mg ClH/c16-2-5-9(17)10(18)7(15-5)4-1-12-8-6(4)13-3-14-11(8)19SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet derived growth factor receptors (PDGFR), KIT, and fms like tyrosine kinase 3 (FLT 3) (1). SU14813 was developed as a next generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. SU14813 demonstrated broad and potent antitumor activity
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