SR-318 Catalog No.:M28089-C InChi: InChI=1S/C38H40N4O3/c1-25-15-17-26(18-16-25)23-36(43)42(2)35(22-27-19-20-28-9-3-4-10-29(28)21-27)38(45)41-34-14-8-7-13-33(34)40-37(44)31-24-39-32-12-6-5-11-30(31)32/h3-6

InChi: InChI=1S/C38H40N4O3/c1-25-15-17-26(18-16-25)23-36(43)42(2)35(22-27-19-20-28-9-3-4-10-29(28)21-27)38(45)41-34-14-8-7-13-33(34)40-37(44)31-24-39-32-12-6-5-11-30(31)32/h3-6

CAS Number: 900498-44-4

CAS Number: 2123482-78-8

Continuous administration of DS-1001b impairs tumor growth in xenograft mice

ML241 (20 μM) shows no obvious inhibition of the appr 170 kinases tested

SR-318 Catalog No.:M28089-C InChi: InChI=1S/C38H40N4O3/c1-25-15-17-26(18-16-25)23-36(43)42(2)35(22-27-19-20-28-9-3-4-10-29(28)21-27)38(45)41-34-14-8-7-13-33(34)40-37(44)31-24-39-32-12-6-5-11-30(31)32/h3-6SR 318 is a potent and highly selective p38 MAPK inhibitor with IC50s of 5 nM, 32 nM and 6. 11 M for p38, p38 and p38 , respectively. SR 318 potently inhibits the TNF release in whole blood with an IC50 of 283 nM. SR 318 has anti cancer and anti inflammatory activity. Product information CAS Number: 2413286 32 3 Molecular Weight: 459. 58 Formula: C27H33N5O2 Chemical Name: 5 amino N ({4 [(3 cyclohexylpropyl)carbamoyl]phenyl}methyl) 1 phenyl 1H pyrazole