Asciminib osetron Smiles: COC1C=C2N=CN=C(NC3C=C(Cl)C(F)=CC=3)C2=CC=1OCCCCCC(=O)NC(COCC1=CN(CCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)N=N1)C(=O)NCCCCCC(=O)N1CCN(CC1)C(=O)C1=CC(CC2=NNC(=O)C3C=CC=CC2=3)=CC=C1F

Smiles: COC1C=C2N=CN=C(NC3C=C(Cl)C(F)=CC=3)C2=CC=1OCCCCCC(=O)NC(COCC1=CN(CCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)N=N1)C(=O)NCCCCCC(=O)N1CCN(CC1)C(=O)C1=CC(CC2=NNC(=O)C3C=CC=CC2=3)=CC=C1F

4-dichloro-1-benzothiophene-2-carbohydrazide

Perkins MM

Methyl β-D-glucoside

PubMed Central PMCID: PMC4308844

Asciminib osetron Smiles: COC1C=C2N=CN=C(NC3C=C(Cl)C(F)=CC=3)C2=CC=1OCCCCCC(=O)NC(COCC1=CN(CCOCCOCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)N=N1)C(=O)NCCCCCC(=O)N1CCN(CC1)C(=O)C1=CC(CC2=NNC(=O)C3C=CC=CC2=3)=CC=C1FAsciminib (ABL001) is a potent and selective allosteric BCR ABL1 inhibitor, which inhibits Ba F3 cells grown with an IC50 of 0. 25 nM. Product information CAS Number: 1492952 76 7 Molecular Weight: 449. 84 Formula: C20H18ClF2N5O3 Chemical Name: N [4 (chlorodifluoromethoxy)phenyl] 6 [(3R) 3 hydroxypyrrolidin 1 yl] 5 (1H pyrazol 3 yl)pyridine 3 carboxamide Smiles: O[C@H]1CN(CC1)C1N=CC(=CC=1C1C=CNN=1)C(=O)NC1C=CC(=CC=1)OC(F)(F)Cl InChiKey: VOVZXURTCKPRDQ