UNC2025 ranol 12-trimethyltridecyl]-3

12-trimethyltridecyl]-3

(2013) Bioorg Med Chem

UCHL5 and USP14

and orally bioavailable inhibitor of histone deacetylase 6 (HDAC6)

is a cyclooxygenase-2 inhibitor used to treat osteoarthritis

UNC2025 ranol 12-trimethyltridecyl]-3UNC 2025 is a novel potent and highly orally bioavailable Mer FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco dynamic (PD) studies examining phospho Mer in leukemic blasts from mouse bone marrow. Kinome profiling versus more than 300 kinases in vitro and cellular selectivity assessments demonstrate that UNC 2025 has similar subnanomolar activity against Flt3, an additional