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PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM
InChi: InChI=1S/C11H15N5O5/c12-9-6-10(14-3-13-9)16(4-15-6)11(2-18)8(20)7(19)5(1-17)21-11/h3-5
probably by enhancing the interaction between von Hippel-Lindau (VHL) and HIF-1α
21)22)4-23-5-1-2-8(24)6(3-5)14(25)26/h1-3
It plays a critical role in regulating synaptic plasticity and neural network activity
ATP synthase inhibitor 1 Catalog No.:M21187-C PDK4-IN-1 is an anthraquinone derivativeATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1 FO ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels. Product information CAS Number: 1023043 30 2 Molecular Weight: 411. 93 Formula: C17H18ClN3O3S2 Chemical Name: 8 [(5 chlorothiophen 2 yl)sulfonyl] 1 phenyl 1,3,8 triazaspiro[4. 5]decan 4 one Smiles: O=C1NCN(C2C=CC=CC=2)C21CCN(CC2)S(=O)(=O)C1=CC=C(Cl)S1 InChiKey:
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