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InChiKey: ZAZKJZBWRNNLDS-UHFFFAOYSA-N
with Kis of 11
suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a
which are hormones that predominantly affect the metabolism of carbohydrates and
CAS Number: 159997-94-1
Gefitinib impurity 2 Catalog No.:M31681-C InChiKey: ZAZKJZBWRNNLDS-UHFFFAOYSA-NGefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY 50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 246512 44 7 Molecular
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