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Smiles: CN1CCN(CC2=NC3=CC(Cl)=C(CN(CC#C)C4C=CC(=CC=4)C(=O)NCC4=CN=CC=C4)C=C3C(=O)N2C)CC1
apoptosis and ERK activation in A375 cells
which are important signaling molecules in cancer cell metastasis
InChi: InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6
The oral bioavailability of AZD3759 is excellent at 90%
AG-1478 hydrochloride - CAS# 170449-18-0 Size:Contact [email protected] for quotation Smiles: CN1CCN(CC2=NC3=CC(Cl)=C(CN(CC#C)C4C=CC(=CC=4)C(=O)NCC4=CN=CC=C4)C=C3C(=O)N2C)CC1AG 1478 hydrochloride (Tyrphostin AG 1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG 1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Product information CAS Number: 170449 18 0 Molecular Weight: 352. 22 Formula: C16H15Cl2N3O2 Synonym: Tyrphostin AG 1478 hydrochloride NSC 693255 hydrochloride Chemical Name: N (3 chlorophenyl) 6, 7 dimethoxyquinazolin 4 amine