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JC-171 is a selective NLRP3 inflammasome inhibitor
Combretastatin A-1 is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin
3 nM for PDGFRα
Epub 2013 Feb 11
25(12):1883-90
(R)-Elagolix Size:Contact [email protected] for quotation JC-171 is a selective NLRP3Elagolix is a highly potent, selective, orally active, short duration, non peptide antagonist of the gonadotropin releasing hormone receptor (GnRHR) (KD = 54 pM). Target: GnRHin vitro: Elagolix is a short acting, nonpeptide, GnRH antagonist, administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full
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