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(Z)-4-Hydroxytamoxifen (also called 4-OH-TAM)
The activity ofGNE-617 hydrochloride is evaluated on a panel 53 non-small cell lung cancer (NSCLC) cell lines in the presence or absence of 10 μM nicotinic acid
Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering
is a potent and selective Sirt2 inhibitor with IC50 ~140 nM
EHT 1864 (10 and 40 mg/kg/day
GSK-3787 - CAS# 188591-46-0 60167 (Z)-4-Hydroxytamoxifen (also called 4-OH-TAM)GSK 3787, CAS No. 188591 46 0, is a selective and irreversible peroxisome proliferator activated receptor delta (PPARdelta) antagonist with good pharmacokinetic properties. GSK3787 can antagonize PPARbeta delta in vivo, thus providing a new strategy to delineate the functional role of a receptor with great potential as a therapeutic target for the treatment and prevention of disease. Product information CAS Number: 188591 46 0 Molecular Weight: 392.