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ACY-1083 Catalog No.:M18431-C 10-pentaene dihydrochloride

SKU: 47568569855

4.4
USD100.00 USD150.00

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Description

10-pentaene dihydrochloride

for 19 or 11 days

Smiles: CN(C1CC(C)(C)NC(C)(C)C1)C1=CC=C(N=N1)C1=CC=C(C=C1O)C1C=NNC=1

is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells

The uptake by the cortex and cerebellum is rapidly decreased after injection

ACY-1083 Catalog No.:M18431-C 10-pentaene dihydrochlorideACY 1083 is a selective and brain penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260 fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY 1083 effectively reverses chemotherapy induced peripheral neuropathy. Product information CAS Number: 1708113 43 2 Molecular Weight: 348. 35 Formula: C17H18F2N4O2 Chemical Name: 2 [(4,4 difluoro 1 phenylcyclohexyl)amino] N hydroxypyrimidine 5 carboxamide Smiles:

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