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PF-04859989 hydrochloride Catalog No.:M30145-C CAS Number: 86636-92-2

SKU: 51510598552

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Description

CAS Number: 86636-92-2

COCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=CC=CC=CC2=[N+](CCOCCOCCOCCOCCOCCC(O)=O)C3=CC=CC=C3C2(C)C)C(C)(C)C2=CC=CC=C12

Donepezil HCl is a GSK3 and AChE inhibitor and potential σ1 receptor agonist used to treat Alzheimer's disease

but Octreotide alone does not in PCK rats

Wallace JL

PF-04859989 hydrochloride Catalog No.:M30145-C CAS Number: 86636-92-2PF 04859989 hydrochloride is a brain penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC50s of 23 and 263 nM for hKAT II and rKAT II. PF 04859989 hydrochloride is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 M, respectively). Product information CAS Number: 177943 33 8 Molecular Weight: 214. 65 Formula: C9H11ClN2O2 Chemical Name: (3S) 3 amino 1 hydroxy 1,2,3,4 tetrahydroquinolin 2 one

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