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Finerenone 28283 VU0420373 is a potent heme

SKU: 51610171208

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Description

VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10

) results in a significant reduction in lesion size at 28 days in histological assessment

The combination of grape seed proanthocyanidins and Siberian ginseng eleutherosides obviously diminishes the effects of Methotrexate exposure on indices of thymus and spleens in mice

9 μM for Ovcar8

InChiKey: UYGRNXLHKIBHMM-UHFFFAOYSA-N

Finerenone 28283 VU0420373 is a potent hemeFinerenone (BAY 94 8862) is a third generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500 fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease. Product information CAS Number:

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