N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22

H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22

Cornett EM

A-192621 promotes apoptosis in PASMCs

Sulfadimethoxine is a sulfonamide antibiotic

CAS Number: 511-15-9

N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22N Acetyl calicheamicin, CAS No. 108212 76 6, is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic. Calicheamicins target DNA and cause strand scission. Calicheamicins bind with DNA in the minor groove, wherein they then undergo a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1, 4 didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA,