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3-Dihydro-2H-benzo[d]imidazol-2-one Core
Smiles: CC1=CC(NC2N=CC(Cl)=C(NC3=CC=CC=C3S(=O)(=O)C(C)C)N=2)=C(C=C1C1CCNCC1)OC(C)C
Ponatinib (AP24534) potently inhibits native ABL (IC50: 0
CAS Number: 1898283-02-7
Hanqing Dong
PF-06372865 Catalog No.:M14974-2 3-Dihydro-2H-benzo[d]imidazol-2-one CorePF 06372865 is an orally active, 2 3 5 subtype selective GABAA positive allosteric modulator (PAM). PF 06372865 is a high affinity ligand at GABAA receptors containing 1 2 3 5 subunits (Kis of 2. 9 nM, 21 nM, 134 nM for 2, 1 PAM, 2 PAM, respectively), with low affinity for 4 6 subunits. PF 06372865 can across the blood brain barrier (BBB). PF 06372865 has anxiolytic activity and has the potential for epilepsy. Product information CAS Number: 1614245
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