ML786 dihydrochloride Catalog No.:M19993-C Necrotic cell death is determined

Necrotic cell death is determined by measuring lactate dehydrogenase (LDH) release from cells

CAS Number: 14755-02-3

2016 Apr 6

InChi: InChI=1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4

129(8):3121-3133

ML786 dihydrochloride Catalog No.:M19993-C Necrotic cell death is determinedML786 dihydrochloride is a potent and orally bioavailable Raf inhibitor, with IC50s of 2. 1, 4. 2, and 2. 5 nM for V600EB Raf, wt B Raf, and C Raf, respectively. ML786 dihydrochloride also inhibits Abl 1, DDR2, EPHA2, KDR, and RET (IC50=<0. 5, 7. 0, 11, 6. 2, 0. 8 nM). ML786 dihydrochloride can be used for the research of cancers. Product information CAS Number: 1237536 18 3 Molecular Weight: 611. 48 Formula: C29H31Cl2F3N4O3 Chemical Name: (Z) 3 (2