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Imatinib Impurity E PEG3-amine-Boc Smiles: NC1=CC=C(C=C1)C(O)=O

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Description

Smiles: NC1=CC=C(C=C1)C(O)=O

0 mM) inhibited JMJD2A and HG-induced proliferation in a concentration-dependent way

J Biosci Bioeng

such as inflammation and pain

2016 May 1

Imatinib Impurity E PEG3-amine-Boc Smiles: NC1=CC=C(C=C1)C(O)=OImatinib Impurity E is the impurity of Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR ABL, v Abl, PDGFR and c kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS CoV and MERS CoV. Product

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