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N-piperidine Ibrutinib hydrochloride Catalog No.:M30823-C 4 μM for rat smallN piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51. 0 and 30. 7 nM for WT BTK and C481S BTK, respectively. N piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY 133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7. 9 nM. Product information CAS Number: