BIBU 1361 dihydrochloride Catalog No.:M21988-C Solubility: DMSO : < 1

Solubility: DMSO : < 1 mg/mL (insoluble or slightly soluble)

CAS Number: 1566586-52-4

7-4-8-18(14

CAS Number: 73069-27-9

Dexamethasone acetate is an anti-inflammatory glucocorticoid

BIBU 1361 dihydrochloride Catalog No.:M21988-C Solubility: DMSO : < 1BIBU 1361 dihydrochloride is a selective inhibitor of epidermal growth factor receptor (EGFR) kinase with an IC50 value of 0. 038 0. 007 M [1, 2]. The EGFR signaling pathway is associated with multiple intracellular signaling events that promote proliferation and survival. It plays a key role in the progression of glioblastoma multiforme (GBM) . In glioma cells, EGFR signaling can induce the phosphorylation of Akt, Erk1 2 and STAT3. BIBU 1361