Decanoyl-RVKR-CMK Catalog No.:M23011-C CN([C@H](C)CCN1CCC(C)CC1)S(=O)(=O)C1C=C(C)C=CC=1

CN([C@H](C)CCN1CCC(C)CC1)S(=O)(=O)C1C=C(C)C=CC=1

Oxolinic acid is a DNA/RNA synthesis inhibitor

ClH/c1-3-19-16-20-15-10-9-13(18)11-14(15)17(2

2011 Jul 15

Hughes DP et al

Decanoyl-RVKR-CMK Catalog No.:M23011-C CN([C@H](C)CCN1CCC(C)CC1)S(=O)(=O)C1C=C(C)C=CC=1Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi trans Golgi secretory pathway. Furin inhibitor I is a selective, irreversible, and cell permeable competitive inhibitor of proprotein convertases, including furin SPC1 (Ki = ~1 nM), SPC2 PC2 (Ki = 0. 36 nM), SPC3 PC1 PC3 (Ki = 2. 0 nM), SPC4 PACE4 (Ki = 3. 6 nM), SPC6 PC5 PC6, and SPC7 LPC PC7 PC8 (Ki = 0. 12 nM)., Because furin activates viral