O-Desmethyl gefitinib D8 Size:Contact [email protected] for quotation InChi: InChI=1S/C28H25FN6O3/c29-21-12-18-17(23-24(27(37)32-26(23)36)20-14-31-22-6-2-5-11-34(20)22)8-7-16-13-30-19(15-35(21)25(16)18)28(38)33-9-3-1-4-10-33/h2

InChi: InChI=1S/C28H25FN6O3/c29-21-12-18-17(23-24(27(37)32-26(23)36)20-14-31-22-6-2-5-11-34(20)22)8-7-16-13-30-19(15-35(21)25(16)18)28(38)33-9-3-1-4-10-33/h2

Formula: C14H7Br3F3N3O4

Bilobalide has recently been found to be a negative allosteric modulator at the GABAA and GABAA-rho receptors

R406 bound to the ATP binding pocket of Syk and inhibited its kinase activity as an ATP-competitive inhibitor (K(i) = 30 nM)

Smiles: OC(=O)/C=C/C1=CC(Br)=C(Br)C(Br)=C1Br

O-Desmethyl gefitinib D8 Size:Contact [email protected] for quotation InChi: InChI=1S/C28H25FN6O3/c29-21-12-18-17(23-24(27(37)32-26(23)36)20-14-31-22-6-2-5-11-34(20)22)8-7-16-13-30-19(15-35(21)25(16)18)28(38)33-9-3-1-4-10-33/h2O Desmethyl gefitinib D8 is a deuterium labeled O Desmethyl gefitinib. O Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O desmethyl gefitinib is dependent on CYP2D6 activity. O desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays. Product information Molecular Weight: 440. 93 Formula: C21H22ClFN4O3 Chemical Name: 4 [(3 chloro 4 fluorophenyl)amino] 6 {3 [(2, 2, 3, 3, 5, 5, 6, 6