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Bafilomycin A1 Catalog No.:M12329-10 Chemical Name: 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate

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Description

Chemical Name: 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate

This suppresses DNA replication and decreases tumor cell proliferation

CAS Number: 21178-57-4

InChiKey: PZEAMYHHAKUANN-UHFFFAOYSA-N

Callicarpa japonica

Bafilomycin A1 Catalog No.:M12329-10 Chemical Name: 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetateBafilomycin A1 is a specific and reversible inhibitor of vacuolar H+ ATPase (V ATPase) with IC50 values of 4 400 nmol mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis. Product information CAS Number: 88899 55 2 Molecular Weight: 622.

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