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causes a dose dependent tumour static effect that can be converted into regressions when combined with MEK1 inhibition
3-dihydroxypropyl)acetamido]-2
Formula: C24H44O2
Ser422 and Ser262
PX-478 was used at 1-10 µM final concentration in various in vitro assays
PS 1145 dihydrochloride 710ROTAC BRD2/BRD4 degrader-1 causes a dose dependent tumourProduct information CAS Number: 1049743 58 9 Molecular Weight: 395. 67 Formula: C17H13Cl3N4O Chemical Name: (Z) N {6 chloro 9H pyrido[3,4 b]indol 8 yl}pyridine 3 carboximidic acid dihydrochloride Smiles: Cl. Cl. O C(=N\C1C=C(Cl)C=C2C=1NC1=CN=CC=C21) C1=CN=CC=C1 InChiKey: QTDCBADLGJZBHP UHFFFAOYSA N InChi: InChI=1S C17H11ClN4O. 2ClH c18 11 6 13 12 3 5 20 9 15(12)21 16(13)14(7 11)22 17(23)10 2 1 4 19 8 10;; h1 9,21H,(H,22,23); 2*1H Technical Data