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Volasertib trihydrochloride (BI 6727 trihydrochloride
InChiKey: BKCJZNIZRWYHBN-UHFFFAOYSA-N
Chemical Name: N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-[(furan-2-yl)methyl]methanesulfonamide
Formula: C22H21FO4
7-dihydroindeno[2
erbB-2 u) Phosphoramidite Volasertib trihydrochloride (BI 6727 trihydrochlorideerbB 2 is a transmembrane, tyrosine kinase (TK) receptor whose overexpression is associated with adverse prognosis in breast cancer1. The human epidermal growth factor receptor (erbB 2) is a transmembrane receptor that is overexpressed in 15%25% of breast cancers. erbB 2 overactivity is associated with adverse biological characteristics and poor clinical outcomes1. Overexpression of erbB2 in cell lines leads to transformation in the absence of a
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