Larotrectinib sulfate 775riflophenone 3-C-glucoside Smiles: OC(=O)C1=CC(I)=CC=C1NC(=O)[C@H](CC1C=CC=CC=1)NCC1C=CC=CC=1

Smiles: OC(=O)C1=CC(I)=CC=C1NC(=O)[C@H](CC1C=CC=CC=1)NCC1C=CC=CC=1

2017 Aug 8

271(3):1483-8

Coniglio SJ

InChi: InChI=1S/C25H21N5O3S/c1-30-15-20(13-28-30)19-11-23-24(27-12-19)8-7-18-6-5-17(10-22(18)25(23)31)16-34(32

Larotrectinib sulfate 775riflophenone 3-C-glucoside Smiles: OC(=O)C1=CC(I)=CC=C1NC(=O)[C@H](CC1C=CC=CC=1)NCC1C=CC=CC=1Larotrectinib sulfate (LOXO 101 sulfate; ARRY 470 sulfate) is an ATP competitive oral, selective inhibitor of the tropomyosin related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). Product information CAS Number: 1223405 08 0 Molecular Weight: 526. 51 Formula: C21H24F2N6O6S Chemical Name: (3S) N {5 [(2R) 2 (2,5 difluorophenyl)pyrrolidin 1 yl]pyrazolo[1,5 a]pyrimidin 3 yl} 3