Antihistamine-1 ifan Smiles: CC(=O)CC(C1=C(O)C2=CC=CC=C2OC1=O)C1C=CC=CC=1

Smiles: CC(=O)CC(C1=C(O)C2=CC=CC=C2OC1=O)C1C=CC=CC=1

UNC926 also exhibits a low micromolar affinity for the close homolog

GLPG-3221 can be uesd for the treatment of cystic fibrosis

XCT790 is a selective ERRα antagonist/inverse agonist (IC50 = ~400 nM)

CAS Number: 31282-04-9

Antihistamine-1 ifan Smiles: CC(=O)CC(C1=C(O)C2=CC=CC=C2OC1=O)C1C=CC=CC=1Antihistamine 1 is a H1 antihistamine (Ki=6. 9 nM) with acceptable blood brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5. 4 and 0. 8 M, respectively. Product information CAS Number: 1186430 60 3 Molecular Weight: 389. 47 Formula: C23H24FN5 Chemical Name: 1 [(4 fluorophenyl)methyl] 2 [4 (4 methyl 1H pyrazol 1 yl)piperidin 1 yl] 1H 1,3 benzodiazole Smiles: CC1C=NN(C=1)C1CCN(CC1)C1=NC2=CC=CC=C2N1CC1C=CC(F)=CC=1