Z-Asp-CH2-DCB - CAS# 153088-73-4 Size:2mg solid InChi: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7

InChi: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7

and vasculopathy in experimental systemic sclerosis models

4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone

This agent enhances the accumulation of single and double strand DNA breaks and promotes genomic instability eventually leading to apoptosis

Chemical Name: 2-(5-chloro-2-{[3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)-N-cyclopropyl-1-benzothiophene-4-carboxamide trihydrochloride

Z-Asp-CH2-DCB - CAS# 153088-73-4 Size:2mg solid InChi: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7Z Asp CH2 DCB is an irreversible broad spectrum caspase inhibitor. Z Asp CH2 DCB also inhibits proteases with caspase like activity. Z D CH2 DCB blocks the production of IL 1, TNF , IL 6, and IFN in staphylococcal enterotoxin B (SEB) stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB 1 stimulated T cell proliferation in a dose dependent manner. Z Asp CH2 DCB prevents SU5416 induced septal cell apoptosis and emphysema development.