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K145 is a selective sphingosine kinase-2 (SphK2) inhibitor and anticancer agent
Smiles: COC1C=C(C=CC=1)C1C=NC2=C(C=NN2C=1N)C1=CN=CC=C1
an active natural flavone derivative found in various plant sources
in some chemotherapy regimens as it appears to cause fewer side-effects
synovial hyperplasia
PF-AKT400 omanol 293B K145 is a selective sphingosinePF AKT400 is a broadly selective, potent, ATP competitive Akt inhibitor, displays 900 fold greater selectivity for PKB (IC50=0. 5 nM) than PKA (IC50=450 nM). Product information CAS Number: 1004990 28 6 Molecular Weight: 400. 43 Formula: C20H22F2N6O Chemical Name: N {[(3S) 3 amino 1 {5 ethyl 7H pyrrolo[2,3 d]pyrimidin 4 yl}pyrrolidin 3 yl]methyl} 2,4 difluorobenzamide Smiles: CCC1=CNC2=NC=NC(=C21)N1C[C@@](N)(CNC(=O)C2=CC=C(F)C=C2F)CC1 InChiKey:
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