AT9283 Catalog No.:M10934-10 Tiotropium Bromide hydrate (BA 679BR)

Tiotropium Bromide hydrate (BA 679BR) is a monohydrate of tiotropium bromide (Spiriva

at a dose of 50 mg/kg

and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier

2Na/c8-7(9)5-1-3-6(4-2-5)13-14(10

and 30 mg/kg

AT9283 Catalog No.:M10934-10 Tiotropium Bromide hydrate (BA 679BR)AT9283 is a multikinase inhibitor, is also a small molecule inhibitor of several kinases with potential antineoplastic activity. Multikinase inhibitor AT9283 binds to and inhibits Aurora kinases A and B, JAK2 (Janus kinase 2) and the kinase BCR ABL, which may result in the inhibition of cellular division and proliferation and the induction of apoptosis in tumor cells that overexpress these kinases. Aurora kinases are serine threonine kinases that play