AZ876 displays 25-fold and 2
and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases
Rodríguez-Arias M
PRN1008 is a reversible covalent inhibitor of Bruton’s Tyrosine Kinase (BTK)
48 hours) inhibits BTK-transformed Ba/F3 cell proliferation with an IC50 of 11
Glucocorticoid receptor agonist-1 Size:Contact [email protected] for quotation AZ876 displays 25-fold and 2Glucocorticoid receptor agonist 1 is a potent glucocorticoid receptor agonist with an IC50 of 2. 8 nM extracted from patent WO2017210471A1, compound 41. Product information CAS Number: 2166375 82 0 Molecular Weight: 569. 69 Formula: C35H39NO6 Chemical Name: (1S,2S,4R,6R,8S,9S,11S,12S,13R) 6 {4 [(3 aminophenyl)methyl]phenyl} 11 hydroxy 8 (2 hydroxyacetyl) 9,13 dimethyl 5,7 dioxapentacyclo[10. 8. 0. 0,. 0,. 0,]icosa 14,17 dien 16 one Smiles: