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SKF89976A (100 μM) reversibly reduces GAT currents in every studied cell by 67
Chemical Name: 6-(3-fluorophenyl)-N-[1-(2
6 μmol/L) increases the formation of DNA-protein complexes in a time-dependent manner
InChi: InChI=1S/C25H25N3O3/c1-4-31-21-15-18(8-10-20(21)30-3)23(28-22-14-16(2)11-13-26-22)19-9-7-17-6-5-12-27-24(17)25(19)29/h5-15
InChi: InChI=1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38
CU-3 aflumizone SKF89976A (100 μM) reversibly reducesCU 3 is the racemate of (5Z,2E) CU 3. (5Z,2E) CU 3 is a potent and selective inhibitor against the isozyme of DGK with an IC50 value of 0. 6 M, competitively inhibits the affinity of DGK for ATP with a Km value of 0. 48 mM. (5Z,2E) CU 3 targets the catalytic region, but not the regulatory region of DGK. (5Z,2E) CU 3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells. Product information CAS
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