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selective and orally bioavailable γ-secretase inhibitor with an IC50 of 0
28(43-6)26(33)37)27(21)44-29(38)17-10-8-7-9-11-17)32-20(41-4)12-19(36)30(15-40-3)14-34(2)25(32)22(33)23(42-5)24(30)32/h7-11
on platelet and renal prostaglandin-endoperoxide metabolism
Smiles: [N-]=[N+]=NC1C=CC=C(CC(N)C(O)=O)C=1
PF-06670910
Pitofenone hydrochloride Catalog No.:M18086-C selective and orally bioavailable γ-secretasePitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 M, respectively. Product information CAS Number: 1248 42 6 Molecular Weight: 403. 90 Formula: C22H26ClNO4 Chemical Name: methyl 2 {4 [2 (piperidin 1 yl)ethoxy]benzoyl}benzoate hydrochloride Smiles: Cl. COC(=O)C1=CC=CC=C1C(=O)C1=CC=C(C=C1)OCCN1CCCCC1 InChiKey: ZRFIFDFEDPJBII UHFFFAOYSA