USP25/28 inhibitor AZ1 oid-binding protein(668-687) TFA attenuates atopic dermatitis-like skin lesions

attenuates atopic dermatitis-like skin lesions induced by 2

this agent is highly polyglutamylated and competes for the folate binding site of DHFR

93(2):146-7

inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo

CAS Number: 19046-60-7

USP25/28 inhibitor AZ1 oid-binding protein(668-687) TFA attenuates atopic dermatitis-like skin lesionsUSP25 28 inhibitor AZ1 (AZ1) is an orally active, selective, noncompetitive, dual ubiquitin specific protease (USP) 25 28 inhibitor with IC50s of 0. 7 M and 0. 6 M, respectively. USP25 28 inhibitor AZ1 attenuates colitis and tumorigenesis in the mice model. Product information CAS Number: 2165322 94 9 Molecular Weight: 422. 21 Formula: C17H16BrF4NO2 Chemical Name: 2 {[(5 bromo 2 {[4 fluoro 3 (trifluoromethyl)phenyl]methoxy}phenyl)methyl]amino}ethan 1