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Madrasin stalls spliceosome assembly at the A complex
Dihydroethidium
InChiKey: NJYVEMPWNAYQQN-UHFFFAOYSA-N
Cristofoletti R
Triptonide
ONO-AE3-208 Size:Solid 2 mg Madrasin stalls spliceosome assembly atONO AE3 208 is a potent n EP4 antagonist (Ki = 1. 3 nM). ONO AE3 208 suppresses cell invasion, migration, and metastasis of prostate cancer. The in vitro cell invasion and migration were suppressed by ONO AE3 208 in a dose dependent manner without affecting cell proliferation. The in vivo bone metastasis of PC3 was also suppressed by ONO AE3 208 treatment. EP4 expression levels were correlated with prostate cancer cell invasiveness and EP4 specific
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