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Beclomethasone 17-propionate Catalog No.:M31928-C InChi: InChI=1S/C49H74Br2N6O11/c1-12-30(6)42(35(67-10)27-37(59)56-25-19-22-34(56)43(68-11)31(7)44(60)52-33(49(65)66)26-32-20-15-13-16-21-32)55(9)48(64)40(28(2)3)53-45(61)41(29(4)5)54(8)36(58)23-17-14-18-24-57-46(62)38(50)39(51)47(57)63/h13

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Description

InChi: InChI=1S/C49H74Br2N6O11/c1-12-30(6)42(35(67-10)27-37(59)56-25-19-22-34(56)43(68-11)31(7)44(60)52-33(49(65)66)26-32-20-15-13-16-21-32)55(9)48(64)40(28(2)3)53-45(61)41(29(4)5)54(8)36(58)23-17-14-18-24-57-46(62)38(50)39(51)47(57)63/h13

acts as a TRPA1 covalent and TRPV1 non-covalent agonist

2 μM for promoter activity of the MITF target gene TRPM-1

Chemical Name: 5-ethyloxolan-2-one

no other kinases are inhibited by more than 20% at 1 μM EAI045

Beclomethasone 17-propionate Catalog No.:M31928-C InChi: InChI=1S/C49H74Br2N6O11/c1-12-30(6)42(35(67-10)27-37(59)56-25-19-22-34(56)43(68-11)31(7)44(60)52-33(49(65)66)26-32-20-15-13-16-21-32)55(9)48(64)40(28(2)3)53-45(61)41(29(4)5)54(8)36(58)23-17-14-18-24-57-46(62)38(50)39(51)47(57)63/h13Beclomethasone 17 propionate (Beclomethasone 17 monopropionate), an active metabolite of Beclomethasone dipropionate (HY 13571), is a glucocorticoid receptor (GR) agonist. Beclomethasone 17 propionate exhibits greater affinity for GR than Beclomethasone dipropionate. Beclomethasone 17 propionate effectively suppresses cytokine production in chronic obstructive pulmonary disease (COPD) lung macrophages. Product information CAS Number: 5534 18 9

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