Syk-IN-1 7749944 7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-ol

7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-ol

48 or 72 hours) induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells

Cleton-Jansen AM

interference of MITF with ML-329 will be useful in characterizing the specific roles of MITF in melanoma and validate blockade of MITF function as a potential treatment of melanoma

Smiles: OC(=O)CCOCCOCCOCCOCCS(O)(=O)=O

Syk-IN-1 7749944 7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-olSyk IN 1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM. Product information CAS Number: 1491150 77 6 Molecular Weight: 366. 42 Formula: C18H22N8O Chemical Name: 3 {[(1R,2S) 2 aminocyclohexyl]amino} 5 [(1H indol 7 yl)amino] 1,2,4 triazine 6 carboxamide Smiles: NC(=O)C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC1=CC=CC2C=CNC=21 InChiKey: FPQNRXITKTZFMF NWDGAFQWSA N InChi: InChI=1S C18H22N8O c19 11 5 1 2 6 12(11)23 18 24 17(15(16(20)27)25 26 18)22