Masitinib Size:2mg solid Smiles: C1SC2=CC=CC=C2C2NC3=CC=CC=C3C=21

Smiles: C1SC2=CC=CC=C2C2NC3=CC=CC=C3C=21

PubMed PMID: 16515549

Acalabrutinib (100 mg twice per day) assessed for thrombus formation at injured arterioles of the mice

Smiles: CCN(CC)C1C=CC(/C=N/NC(=O)C2C=CC(O)=CC=2)=CC=1

Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle

Masitinib Size:2mg solid Smiles: C1SC2=CC=CC=C2C2NC3=CC=CC=C3C=21Masitinib, also known as AB1010, is an orally bioavailable and multi targeted protein tyrosine kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds to and inhibits both the wild type and mutated forms of the stem cell factor receptor (c Kit; SCFR); platelet derived growth factor receptor (PDGFR); fibroblast growth factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As a consequence, tumor