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InChi: InChI=1S/C30H25F10NO3/c1-14(2)22-11-23(25(43-4)12-24(22)31)21-6-5-18(28(32
2 uM) with similar
H2073 (WT)
Data Brief
subcutaneous injection) to mice bearing GM-CSF-secreting B16 tumors
CH223191 - CAS# 301326-22-7 0258 InChi: InChI=1S/C30H25F10NO3/c1-14(2)22-11-23(25(43-4)12-24(22)31)21-6-5-18(28(32CH223191, CAS No. 301326 22 7, is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. CH223191 can prevent 2, 3, 7, 8 TCDD induced toxicity by antagonizing the aryl hydrocarbon receptor. 2, 3, 7, 8 Tetrachlorodibenzo p dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD induced AhR
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