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increases proliferation of mouse bone marrow stromal cells and osteoblasts
there is no major decrease in mitochondrial import receptor subunit TOM20 homolog (TOMM20) or in the cytoskeleton protein β-actin
Formula: C15H17ClN4O4
Smiles: CNS(=O)(=O)C1=CC=C(CCNC(=O)C2=CC(Cl)=CC=C2OC)C=C1
February 1966
G5-7 tanediol increases proliferation of mouse boneG5 7, an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5 7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5 7 has the potential for glioma study. Product information CAS Number: 939681 36 4 Molecular Weight: 411. 44 Formula: C24H23F2NO3 Chemical Name: tert butyl (3Z,5Z) 3,5 bis[(2 fluorophenyl)methylidene] 4
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