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Treatment with 100 nM dBET6 leads to degradation of BRD4 after 1 hr
JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT)
Solubility: DMSO: 50 mg/mL(114
04 μM in MG63 cell lines
competitive antagonist of BLT2 receptors (IC50 values are ~ 1 and > 10 μM at human recombinant BLT2 and BLT1 receptors respectively)
CDK-IN-2 - CAS# 1269815-17-9 C-0994 Treatment with 100 nM dBET6CDK IN 2 is a potent and specific CDK9 inhibitor with IC50 of Product information CAS Number: 1269815 17 9 Molecular Weight: 363. 81 Formula: C18H19ClFN3O2 Synonym: CDK inhibitor II Chemical Name: (3R) N [5 chloro 4 (5 fluoro 2 methoxyphenyl)pyridin 2 yl]piperidine 3 carboxamide Smiles: COC1=CC=C(F)C=C1C1=CC(NC(=O)[C@H]2CNCCC2)=NC=C1Cl InChiKey: AHMKHNVZGOQLRQ LLVKDONJSA N InChi: InChI=1S C18H19ClFN3O2 c1 25 16 5 4 12(20)7 14(16)13 8 17(22 10
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